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A Florida woman with paroxysmal nocturnal hemoglobinuria (PNH), a rare autoimmune disease, suffered serious complications that required multiple vaccinations before receiving blood. Alexis Lorentz, 23, suffers from the disease, which affects around one in a million people. According to the New York Post, the immune system attacks and destroys red blood cells, requiring blood transfusions to "replace" the "damaged red blood cells." However, the report states that when he arrived at UCI Medical in California, doctors told him that a blood transfusion was not possible without simultaneous vaccinations against tetanus, pneumonia and meningitis. Within minutes of being vaccinated, Lorentz experienced warning signs, including temporary blindness, vomiting and significant bruising and swelling. The incident sparked widespread debate about the reasons for compulsory vaccination in hospitals and the potential risks associated with it. New reports have emerged that Lorentz has seriously injured his ear and is fighting for his life.

Autoimmune diseases involve an overactive or malfunctioning immune system and can respond abnormally to vaccines. The benefits of simultaneous vaccination with multiple vaccinations include comprehensive protection against multiple infections in one session. This is especially important for people with weakened immune systems. However, such patients are at increased risk because their immune systems may overreact and cause or worsen an underlying autoimmune disease. The immune system can mistakenly attack healthy cells in response to vaccines, causing complications such as inflammation, allergic reactions and even cytokine storms (severe immune reactions). Although research generally supports the safety of vaccines for most autoimmune patients, it is important to assess a person's health status and underlying medical conditions before administering multiple vaccines.

Cytokines help fight infections, but during a cytokine storm, overproduction of cytokines can cause severe inflammation and tissue damage. After vaccination, some people with rare autoimmune diseases may be at higher risk of experiencing a cytokine storm due to an overactive immune system. The exact mechanism of this vaccine can cause the body to attack its own cells, causing symptoms such as high fever, organ damage and, like a Florida woman, causes blindness and bruising. which in severe cases can be life-threatening.

Special vaccinations may be recommended for patients with rare diseases, particularly those requiring blood transfusions. Patients who are immunocompromised or who receive frequent blood transfusions may require vaccinations such as hepatitis B or pneumococcal vaccine before blood transfusions. For autoimmune diseases, physicians should carefully consider the risks and benefits of administering vaccines, especially when patients are receiving therapies such as immunosuppressive therapies that complicate the immune response to both vaccines and infections. Vaccines provide important protection against disease, but special caution is required when vaccinating patients with autoimmune diseases or rare diseases. Individual immune status, vaccination schedules and potential risks should be carefully managed, and healthcare professionals should be alert for signs of complications such as cytokine storms and adverse autoimmune reactions.